Historical background for the maternal PKU syndrome.
نویسنده
چکیده
OBJECTIVE To provide information on the history of maternal phenylketonuria. METHODS A review of the literature and personal observations were conducted. RESULTS Compilation of sequential information about the development of our understanding of maternal PKU was produced. CONCLUSIONS The history of maternal PKU reflects continuous additions to our understanding of this teratogenic syndrome.
منابع مشابه
Reply to SP Bessman
Bessman’s historical perspective in this issue (1) provides us with an interesting summary of one side of a controversy that occurred > 20 y ago concerning a possible role for tyrosine in the mental defect of phenylketonuria (PKU) and maternal PKU. Unfortunately, his editorial confuses the difference between early-treated and late-treated PKU. The study by Hsia et al (2) was conducted in instit...
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ورودعنوان ژورنال:
- Pediatrics
دوره 112 6 Pt 2 شماره
صفحات -
تاریخ انتشار 2003